Zombie Cell Cleanser - Senolytic Pen (3ml)

Zombie Cell Cleanser | 3ml Pre-Mixed Pen is a stabilized formula combining 10mg of fisetin – a natural flavonoid with senolytic activity – and 30 billion exosomes derived from MUSE MSC stem cells. The formula is pre-mixed and distributed into 300 units, designed for research applications focused on eliminating senescent cells, enhancing tissue regeneration, and restoring cellular communication.

Senescent cells – also known as "zombie cells" – are metabolically active but non-functional cells that accumulate in the body with age and chronic inflammation. They secrete harmful signals (SASP) that damage surrounding tissues, suppress regeneration, and accelerate aging processes. Zombie Cell Cleanser is developed to target and eliminate these cells, while also providing regenerative support through exosomes carrying active RNAs, microRNAs, and proteins that assist in recovery processes.

What makes this formula unique?

Zombie Cell Cleanser combines two completely different yet synergistically acting molecules – fisetin, which exhibits senolytic effects on damaged and aging cells, and exosomes from MUSE MSC, which stimulate regeneration through intercellular communication reactivation. This makes the product particularly suitable for research models of cellular aging, post-injury recovery, and chronic inflammation.

Fisetin acts as a natural agent that clears damaged cells by inducing apoptosis (programmed cell death) in senescent cells without affecting healthy tissue. Studies show that it acts on pathways related to p53, p21, and BCL-2, helping restore tissue homeostasis and reduce systemic inflammation.

The exosomes in the formula are derived from MUSE MSC – a unique type of stem cell with both regenerative and anti-inflammatory profiles. These exosomes transport signaling molecules required to reactivate repair processes, improve microcirculation, stimulate neovascularization, and promote cellular differentiation.

Key Components and Mechanism of Action

Fisetin (10mg)

Fisetin is a polyphenolic flavonoid found in fruits like strawberries and apples, known for its powerful senolytic activity. Unlike many antioxidants, fisetin selectively eliminates damaged and non-functional cells by suppressing SASP (senescence-associated secretory phenotype), reducing inflammation, and restoring proper cellular signaling. Research shows that fisetin may improve cognitive function, support vascular elasticity, and reduce the risk of age-related chronic conditions.

Exosomes from MUSE MSC (30 Billion)

Exosomes are nanovesicles measuring 30–150 nm in diameter, carrying bioactive "cargo" of RNAs, proteins, and lipids specific to the donor cell. MUSE MSC cells are known for their unique ability to withstand cellular stress and directly differentiate into damaged tissues. Exosomes derived from them help restore intercellular communication, promote cellular migration, and reduce local inflammation, acting as highly precise biological signaling systems.

By combining cleansing and restorative functions, Zombie Cell Cleanser offers an innovative two-phase approach to addressing cellular aging—removing harmful cells and activating a new, functional tissue environment.

Synergistic Effect of the Formula

The formula of Zombie Cell Cleanser is designed to achieve a dual-phase effect:

1. Selective elimination of senescent cells (via fisetin) – which frees tissues from inflammatory and non-functional cells that block regeneration.
2. Molecular rebooting of tissue regulation (via MUSE MSC exosomes) – which "restore communication" between cells and activate natural regenerative signals.

This approach offers a unique model of biological cleansing and restoration, going far beyond the effects of traditional antioxidant or anti-inflammatory agents. The combination of selectivity, precision, and regenerative intelligence makes Zombie Cell Cleanser a unique tool in the context of modern senolytic biology.